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Emeritus Professor / Hamdallah Hafez Ali Zedan
Microbiology and Immunology
hamdallah.zidan@pharma.cu.edu.eg

Latest List of Publications

LIST OF PUBLICATIONS
(Prof. Dr. Hamdallah Zedan)

1. A. M. Taha, M. M. Aboulwafa, H.Zedan, O. M. Helmy (2022).
Ramucirumab combination with sorafenib enhances the inhibitory effect of sorafenib on HepG2 cancer cells.
Scientific Reports (2022). Accepted for publication.

2. M. Aboulwafa , R. Hassan, M. Abdel-Hakeem, H.Zedan (2023).
Etanercept and Infliximab, two tumor necrosis factor-α (TNF-α) inhibitors with different action profiles: An in vitro and in vivo study in the context of reviewed therapeutic applications.
Biointerface Research in Applied Chemistry (2023). Accepted for publication.

3. Mohamed SH, Hady OA, Kashef MT, Zedan HH. (2022). Antivenoms, hepatitis B vaccine and oral polio vaccine can be considered for storage and handling outside the cold chain following the innovative ‘controlled temperature chain’ approach.
Biologicals (2022). Accepted for publication.

4. Abulmagd S, Khattab AA , Zedan H (2022). Expression of full and fragment-B of diphtheria toxin genes in Escherichia coli for generating of recombinant diphtheria vaccines.
Clin Exp Vaccine Res 11(1):12-29
https://doi.org/10.7774/cevr.2022.11.1.12

5. Kilany LA, Gaber AA, Aboulwafa MM, Zedan HH (2021). Therapeutic Monoclonal Antibodies: Future Prospectives
J Cancer Immunol. 3(4):177-182.
https://www.scientificarchives.com/admin/assets/articles/pdf/therapeutic-monoclonal-antibodies-future-prospectives-20211126101135.pdf

6. Omar, S, H.H. Zedan and T. M. Ibrahim (2021). Quorum sensing inhibitory effect of bergamot oil and aspidosperma extract against Chromobacterium violaceum and Pseudomonas aeruginosa.
Archives of Microbiology (2021) 203:4663–4675
https://doi.org/10.1007/s00203-021-02455-8
Published online 27 June 2021

7. Kilany LA, Gaber AA, Aboulwafa MM, Zedan HH. Trastuzumab immunogenicity development in patients’ sera and in laboratory animals. BMC Immunology. 2021 Dec;22(1):1-15.
https://doi.org/10.1186/s12865-021-00405-z

8. Elshimy R, H. Zedan, Tarek H. Elmorsy, R. A. Khattab (2021). A study on multidrug-resistant E. coli clinical isolates from greater Cairo area hospitals. Microbial Drug Resistance 27(10)1420-1432
Published on line on 26 May 2021.
DOI: 10.1089/mdr.2020.0521.

9. Sheraba, N.S., A.S. Yassin, M.R. Diab, M.A. Amin, Y.Alhamhoom and H. H. Zedan (2020). An Efficient Method for Endotoxin Removal from Snake Antivenoms: A Comparative Study of Different Chromatography Techniques.
Chromatographia (2020) 83:779–787
https://doi.org/10.1007/s10337-020-03887-y

10. El Korany S.M., O.M.Helmy, A. M. El Halawany, Y. E.Ragab, H.Zedan (2020). Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate
BMC Biotechnology 20 (1), 1-16

11. Sheraba, N.S., A.S. Yassin, M.R. Diab, M.A. Amin and H.H.Zedan (2019). A Validation study of the Limulus Amebocyte Lysate test as end-product endotoxin test for polyvalent horse snake antivenom. PDA J Pharm Sci Technol.73 (6) 562-571
https://doi.org/10.5731/pdajpst.2018.009522

12. El Nabi, H.E.A., N. M. Saleh, H. Zedan (2019). Correlation of efflux pumps expression in carbapenem resistance Acinetobacter baumannii: Synthetic and natural efflux pump inhibitors as therapy approach.
ASM/ESCMID Conference on Drug Development to Meet the Challenge of Antimicrobial Resistance, September 3-6, 2019 in Boston, MA.

13. Helal H.S., A. Hanora, R. A. Khattab, H. Hamouda and H. Zedan (2018). Mining of Egypt’s Red Sea invertebrates for potential bioactive producers. Biotechnology Letters. 40 (11-12):1519-1530 https://doi.org/10.1007/s10529-018-2600. Published on line 17 August 2018.

14. Elshimy R, R. A. Khattab, H. Zedan, A.S.Hosny and Tarek H. Elmorsy (2018).Study on prevalence and genetic discrimination of methicillin-resistant Staphylococcus aureus (MRSA) in Egyptian hospitals. Afr. J. Microbiol. Res. 12(27):629 – 646.

15. Ahmed M.A, H. Zedan, R. Aziz, O. Helmy, Y. Tanriver (2018). A contribution to the study of natural killer cells development in selected murine lymphoid tissues. In preparation.

16. Ghattas M.Z., Elrakaiby M.T., Aziz R.K., Zedan H.H.(2017). Staphostatins as genetic biomarkers to differentiate Staphylococcus aureus from Staphylococcus epidermidis in clinical isolates and nasal microbiome samples. In Dent, L.L., Mandape, S.N., Pratap, S. et al. Proceedings of the 16th Annual UT-KBRIN Bioinformatics Summit 2016: proceedings. BMC Proc 11, 9 (2017). https://doi.org/10.1186/s12919-017-0078-5

17. Abdeldayem A, H. Zedan , A. Badr , A. Fahmy , M. Akmal (2016).In vitro evaluation of anticancer activity of 5-fluorouracil and curcumin in single and combined forms against breast and colon cancer cell lines. International Journal of Advanced Research 4(6): 1649-1657.

18. Aboleil A. and Zedan, H. (2015). Synthesis, cloning and expression of a novel pre-‎miniproinsulin analogue gene in Escherichia coli. Journal of Advanced Research 6:663– 667.

19. Sheraba, N.S., A.S. Yassin, M.R. Diab, M.A. Amin and H. Zedan (2015). Quality control testing for tracking endotoxin producing Gram negative bacteria during ‎the preparation of polyvalent snake antivenom immunoglobulin. ‎PDA J.Pharm.Sci.Tech. 69:499-510.

20. Sheraba, N.S., A.S. Yassin, M.R. Diab, M.A. Amin and H. Zedan (2014). Detection of endotoxin producing Gram negative bacteria through an environmental ‎monitoring program applied in an antisera production plant. Egypt. J. Biomed. Sci. 38: 211-224.

21. Zedan, H. (2014). Overview of Egypt’s Biodiversity Status and Trends. Report for EEAA, Egyptian Ministry of the Environment.

22. Zedan H. (2014(. Recent advances in vaccine development. Second International Conference on Basic and Applied Sciences, 2-4 April 2014, Sokhna, ‎Egypt.‎

23. Helal H.S., Salah El-DinT. A., Ali A. E,Hamouda H.H., Zedan H. (2014). Tobramycin-silver nanocomposite: a new trend of antimicrobials against resistantstrains. J. Pharm. Biol. Sci. 9(3):54 – 61.

24. Salem M.H., G. G. Zhanel, H. Zedan and A. M. Noreddin (2014). Evaluation of Telavancin, Daptomycin, Tigecycline, Linezolid, and Vancomycin Pharmacodynamics against MRSA Isolates Collected in the Canadian-Ward (CAN-Ward) Surveillance Study: A Monte Carlo Simulation Analysis. The American Association of Pharmaceutical Scientists Annual Meeting, 3-6 November 2014, San Diego, California, USA.

25. Issa A. H., Shaaban, M., H. Zedan, A. Fahmy (2014). Evaluation of the effects of aluminum phosphate and calcium ‎phosphate nanoparticles as adjuvants in vaccinated mice.International Journal of Chemical Engineering and ‎Applications 373-5:367 .

26. Zedan,H., N. El Kholy, A. Barakat, M. Zaki (2014). Genetic mutations in influenza viruses and its relation to drug resistance. Ain Shams Univ.J. Environment. Stud. 10: 123-132.
27. Hashem, R., M. Amin and H. Zedan(2013). Fluoroquinolone resistance mechanisms in methicillin-resistant Staphylococcus aureus clinical isolates from two major hospitals in Cairo, Egypt. Journal of Infection in Developing Countries 7: 796-803.

28. Yassin A. et al (2013). Antibiotic resistance patterns among common Gram positive and Gram negative pathogens in clinical isolates from major hospitals in Cairo, Egypt. In “Worldwide Efforts in Fighting against Microbial pathogens: From Basic Research to Technological Developments”, A. Mendez-Vilas (ed.), Brown Walker Press, Florida, pp34-39.

29. Sheraba, N.S., A.S. Yassin, M.R. Diab, M.A. Amin and H. Zedan (2013). Determination of possible sources of endotoxin contamination during different steps of antisera production, Fourth International Scientific Conference of Faculty of Pharmacy, Cairo University, Cairo, Egypt, 24-25 April 2013.

30. Ali, M., H. Zedan and A. Kholafi (2012).Evaluation of viability of BCG vaccine using a conventional count method and MTT assay. Egypt. J. Biomed. Sci. 36: 151-139

31. Zedan, H., Z. N. Said, M.S. Zaki and R. El Far (2011). Study of the prevalence of occult HBV infection among hemodialysis Egyptian patients Med. J. Teach. Hospitals &Instit. 24(30): 361-376.

32. Elmoghazy, M., H. Zedan , A.E. Ali (2011). Study of the effectiveness of selected chemical agents used for disinfection of industrial water purification systems. Egypt. J. Biomed. Sci. 35:248 – 262

33. Zedan, H. (2005). The Role of the Convention on Biological Diversity and its Protocol on Biosafety in Fostering the Conservation and Sustainable Use of the World’s Biological Wealth for Socio-economic and Sustainable Development. J. Indust. Microbiol. Biotech. (USA) 32 : 496 -501

34. Zedan, H. (2005). Patents and Biopiracy: The Search for Appropriate Policy and Legal Resources. Brown Journal of World Affairs (USA) 63: 45-58

35. Zedan, H., P. Deda and J. Mulongoy (2005). The major threats to the conservation and sustainable use of Island biological diversity. Natural Resources Forum: United Nations Sustainable Development Journal 10:11 – 23.

36. Zedan H.(2005). From Kuala Lumpur to Montecatini to Brazil. In ”Protected areas for achieving biodiversity targets”, Zedan H., K. J. Mulongoy, A. Nogueira, J. Fry, S. B.Gidda, P. Deda, D. Ainsworth, M. Régnier (Eds.) (2005), CBD News Special Edition, CBD, UNEP & UN, Montreal.

37. Zedan, H. (2005). Biodiversité et bien être humain. La Synthèse pour la Convention sur la biodiversité biologique. Objectiveterre 7(2) : 6-8.

38. Zedan, H. (ed.) (2005). The impact of trade liberalization on agricultural biological diversity. UN CBD Technical Publication Series 16, UN CBD Secretariat, Montreal, Canada

39. Zedan, H. (ed.) (2005). Working together for biodiversity: regional and international initiatives contributing to achieving and measuring progress towards the 2010 target. UN CBD Technical Publication Series 17, UN CBD Secretariat, Montreal, Canada

40. Zedan, H. (ed.) (2005). Towards effective protected area systems: An action guide to implement the Convention on Biological Diversity programme of work on protected areas. UN CBD Technical Publication Series 18, UN CBD Secretariat, Montreal, Canada

41. Zedan, H. (ed.) (2004). Solutions for sustainable mariculture - avoiding the adverse effects of mariculture on biological diversity. UN CBD Technical Series 12 (January 2004), UN CBD Secretariat, Montreal, Canada, pp54

42. Zedan, H. (ed.) (2004). Technical advice on the establishment and management of a national system of marine and coastal protected areas. UN CBD Technical Series 13 (January 2004), UN CBD Secretariat, Montreal, Canada, pp 43

43. Zedan, H. (ed.) (2004). Biodiversity issues for consideration in planning, establishment and management of protected area sites and networks. UN CBD Technical Publication Series 15, UN CBD Secretariat, Montreal, Canada

44. Zedan, H. (2004). Biodiversity for Food, Nutrition and Health: Double Opportunity or Double Challenge. Faculty Club, McGill University, 13 October 2004, pp 1-10.

45. Zedan, H. (ed.) (2003). Integrated marine and coastal area management approaches for implementation of the Convention on Biological Diversity. UN CBD Technical Publication Series 14, UN CBD Secretariat, Montreal, Canada

46. Zedan, H. (2004). Biodiversity for Food, Nutrition and Health: Double Opportunity or Double Challenge. Faculty Club, McGill University, 13 October 2004.

47. Zedan, H. (ed.) (2003). Status and trends of, and threats to mountain biodiversity and marine, coastal and water ecosystems. UN CBD Technical Publication Series 8, UN CBD Secretariat, Montreal, Canada

48. Zedan, H. (ed.) (2003). Facilitating conservation and sustainable use of biological diversity. UN CBD Technical Publication Series 9, UN CBD Secretariat, Montreal, Canada

49. Zedan, H. (ed.) (2003). Interlinkages between biological diversity and climate change. UN CBD Technical Publication Series 10, UN CBD Secretariat, Montreal, Canada.

50. Zedan, H. (ed.) (2003). Status and trends of biological diversity of inland water ecosystems. UN CBD Technical Publication Series 11, UN CBD Secretariat, Montreal, Canada

51. Zedan, H. (ed.) (2002). Review of the status and trends of, and major threats to, the forest biological diversity, UN CBD Technical Series 7, UN CBD Secretariat, Montreal, Canada.

52. Zedan, H. (2002). The road to the biosafety protocol. In “The Cartagena Protocol on Biosafety. Reconciling Trade in Biotechnology with Environment and Development”. C. Bail, R. Falkrner and H. Marquard, editors, The Royal Institute of International Affairs, Earthscan Publications Ltd., London.

53. Zedan H. (2002). Biodiversity and Sustainable Development, CBD News Supplement, CBD, UNEP & UN, Montreal.

54. Zedan, H. (2002). The road to the biosafety protocol. In “The Cartagena Protocol on Biosafety. Reconciling Trade in Biotechnology with Environment and Development”. C. Bail, R. Falkrner and H. Marquard, editors, The Royal Institute of International Affairs, Earthscan Publications Ltd., London.

55. Zedan, H. (ed.) (2001). Assessment and management of alien species that threaten habitat and species. UN CBD Technical Publication Series 1, UN CBD Secretariat, Montreal, Canada.

56. Zedan, H. (ed.) (2001). Review of the efficiency and efficacy of existing legal instruments applicable to invasive alien species. UN CBD Technical Publication Series 2, UN CBD Secretariat, Montreal, Canada

57. Zedan, H. (ed.) (2001). Assessment of the conservation and sustainable use of forest biodiversity. UN CBD Technical Publication Series 3, UN CBD Secretariat, Montreal, Canada.

58. Zedan, H. (ed.) (2001). The Value of Forest Biodiversity. UN CBD Technical Publication Series 4, UN CBD Secretariat, Montreal, Canada

59. Zedan, H. (ed.) (2001). Impacts of human caused fires on biodiversity and ecosystem functioning and their cause in tropical, temperate and boreal ecosystems. UN CBD Technical Publication Series 5, UN CBD Secretariat, Montreal, Canada

60. Zedan, H. (ed.) (2001). Sustainable management of non-timber forest resources. UN CBD Technical Publication Series 6, UN CBD Secretariat, Montreal, Canada

61. Zedan, H. (1999). The Promise and the Perils of Biotechnology: Regulatory Framework issues. In “Biotechnology and Biosafety” (I. Serageddin and W. Collins, Editors), The World Bank, pp. 44-49.

62. Zedan, H. and Olembo, R. (1999). Biotechnology and Sustainable development: Potential, Prospects and Challenges. In “Environment 2000 and Beyond” (A.K. Hegazy, Ed), Horus Printing Co., Cairo, Egypt.

63. Zedan, H. (1997). Capacity building for safety in biotechnology. In “Transboundary movement of living modified organisms resulting from modern biotechnology: issues and opportunities for policy makers”, (K.L. Mulongoy, Ed.), International Academy of the Environment, Geneva, pp. 69-76

64. Zedan, H. (1994). Loss of plant germplasm: a call for action. In IBPGR /FAO/ IUCN/UNEP "Manual of Plant Germplasm Collection", IBPGR publications.

65. Zedan, H. (1994). Pest Organisms: numbers, ecosystem impact and developing countries needs. In "Identification and Characterization of Pest Organisms" (D.L. Hawksworth, Ed.). C.A. B. International, Wallingford, U.K., pp. 17-35.

66. Zedan, H. (1993). The Economic Value of Microbial Diversity. Industrial Microbiology News (US)43: 178-185.

67. Zedan, H. (1992). Biotechnology Development and Diffusion. In “Biopractice”, ICGEB, Trieste, Italy.

68. Zedan, H. and R. Olembo (1992). Biotechnology Development and Diffusion. Biopractice. 1:22 – 28

69. Attere, F., Zedan, H. and Ng. N.Q. (editors) 1991). Crop Genetic Resources of Africa, Volume I, Ebenezer Baylis, The Trinity Press, U.K.

70. Ng, N. Q, Perrino, P., Attere, F. and Zedan, H. (editors) 1991). Crop Genetic Resources of Africa, Volume II, Ebenezer Baylis, The Trinity Press, U.K.

71. Zedan, H. (1989). Genetic Resources in the Wide Perspective. Proceedings of the workshop on Plant Genetic Resources, International Board for Plant Genetic Resources (IBPGR), Nairobi, Kenya, pp. 20-24.

72. Zedan, H. (1989). "Biological Diversity: a unifying theme". Intergovernmental Panel on Climate Change (IPCC) workshop on Resources Use and Management, Geneva.

73. Zedan, H. (1989). Environmental Applications, and Need for Regulation, of Biotechnology. The First Arab Conference on Perspectives of Modern Biotechnologies in the Arab Countries, Amman (Jordan), March 1989.

74. Zedan, H.H. and R. Olembo (1988). Promotion of Applied Environmental Microbiology in Developing Countries. In `Recent Advances in Biotechnology and Applied Biology', S. Chang and N. Woo (eds.), pp. 75-88.

75. Zedan, H. (1988). Towards Safe and Adequate Biotechnology. Proceedings of the Sixth International Congress of Culture Collections, University of Maryland, Washington, D.C., USA., October 1988, pp. 45-47.

76. Zedan, H. (1988). A Network of Microbiological Resources Centres for Environmental Management and Increased Bioproductivity in Developing Countries. In Perspectives in Environmental Botany, UNESCO, Paris.

77. Zedan, H. (1985). Biological nitrogen fixation in Africa. Proceedings of the First Conference of the African Association For Biological Nitrogen Fixation, Nairobi (pp. 53-58). Zedan, H.H., M. Salama and W.M. Abdel-Rahman (1983). Influence of various pharmaceutical materials on the in vitro antimicrobial bioactivity of nonabsorbable antibiotics. Egypt. J. Pharm. Sci. 24: 121-130.

78. Zedan, H.H., O.M. El-Tayeb and M.N. Walash (1983). Microbial transformation of lucanthone by growing cultures, washed mycelia and non-germinating spores of fungi from Aspergillus group. J. Gen. Microbiol. 129: 1035-1044.

79. Zedan, H.H., M. Salama and W.M. Abdel-Rahman (1983). Relationship between antimicrobial activity of nonabsorbable antibiotics and their in vitro absorption to some pharmaceutical materials. Egypt. J. Pharm. Sci. 24 : 131-137.

80. Zedan, H.H. (1983). Microbiological transformations of steroids. Aromatization of 19-hydroxy-androsta-4,7-diene-3,17-dione into equilin. Egypt. J. Pharm. Sci. 24: 120-132.

81. Zedan, H.H., El-Tayeb and F.F. El-Banna (1982). Microbiological transformations of steroids. VII. Aromatization of 19-nor and 19-hydroxy steroids by washed microbial cells. Bull. Fac. Pharm. Cairo Univ. 19: 110-117.

82. Zedan, H.H., and F.M. Serry (1982). In vitro resistance of microbial contaminants recovered from non-sterile pharmaceuticals and their manufacturing areas. Egypt. J. Pharm. Sci. 23: 33-44.

83. Zedan, H.H. and F.M. Serry (1982) Utilization of various preservatives for growth by microbial contaminants recovered from non-sterile pharmaceuticals and their manufacturing areas. Egypt. J. Pharm. Sci. 23: 45-56.

84. Zedan, H.H. and F.M. Serry (1982). Utilization of p-hydroxybenzoic acid esters combination for growth by microbial contaminants recovered from non-sterile pharmaceuticals and their manufacturing areas. Egypt. J. Pharm. Sci. 23: 57-65.

85. Zedan, H.H. and F.M. Serry (1982). Antimicrobial effectiveness of some preservatives in certain eye and nasal drops. Egypt. J. Pharm. Sci. 23: 66-76.

86. Zedan, H.H. and F.M. Serry (1982). Metabolism of esters of p-hydroxybenzoic acid by a strain of Pseudomonas aeruginosa.Egypt. J. Microbiol. 20: 77-86.
87. El-Bazza, Z., H.H. Zedan, M.A. Toama and O.M. El-Tayeb(1982). Production of aflatoxins by fungi isolated from Egyptian food commodities. Proc. International Symposium on Mycotoxins, Cairo, pp..443-454.

88. Zedan, H.H., O.M. El-Tayeb and F.F. El-Banna (1982). Microbiological transformations of steroids. VIII. Aromatization of 19-nor and 19-hydroxy steroids by non germinating spores of Cylindrocarponradicicola and Fusariumsolani. Bull. Fac. Pharm. Cairo Univ.13: 75-86

89. Badr-elDin, S., H.H. Zedan and A. Abdel-Wahab (1982). Cellulolytic activity of some thermotolerant fungi isolated from Egyptian soil. Egypt. J. Microbiol. 20: 86-98.

90. Zedan, H.H., A. Khatibi, A.A. Salama and O.M. El-Tayeb (1982). Microbial contamination of non sterile raw materials. II. Contamination with bacteria of potential health hazard. Egypt. J. Microbiol. 17: 151-183.

91. El-Bazza, Z., H.H. Zedan, M.A. Toama and O.M. El-Tayeb(1981). Factors affecting aflatoxin production by a localstrain of Aspergillus flavus. Proc. International Symposium onMycotoxins, Cairo, pp. 231-242.

92. Zedan, H.H., A. Hamid and F. Bashir (1981). A feasibility study of radiation sterilization of individual and mixed penicillin G sod., penicillin G procaine and streptomycin sulphate powders in final glass containers. Bull. Fac. Pharm. Cairo Univ. 18: 40-52.

93. Zedan, H.H., M.S. Foda and S.A. Hashem (1981). Distribution and biosynthesis requirements for L-asparaginase activities in bacteria and fungi. Egypt. J. Microbiol. 16: 107-120.

94. Zedan, H.H., M.A. Ahmed, O.M. El-Tayeb and A.K. Ahmedy (1981). Transient bacteremia after teeth extraction: Bacteriological aspect. Proceedings of the International Dental Congress, Cairo, 1981.

95. Ahmed, M, A. and H.H. Zedan (1978). The pattern of sensitivity of oral infections to currently used antibiotics. Egypt. J. Dent. Res. 16: 101-116

96. Foda, M.S., H.H. Zedan and S.A. Hashem (1980). Formation and properties of L-glutaminase and L-asparaginase activities in Pichia polymorpha. ActaMicrobiol. Polon. 2 (4): 343-352.

97. Foda, M.S., H.H. Zedan and S.A. Hashem (1980). Characterization of novel L-asparaginase produced by Rhodotorularubra. Rev. Lat. Amer. Microbiol. 22: 87-95

98. Foda, M.S., H.H. Zedan and S.A. Hashem (1980). Physiology and kinetics of a new L-asparaginase from Arthrobactercitreus. Acta BiologicaIugoslavica (Microbiol.)17: 103-119.

99. Khatibi, A., H.H.Zedan, A.A. Salama and O.M. El-Tayeb (1980). Microbial contamination of non sterile raw materials. I. General Survey. Proc. IVth. Conf. Microbiol., Cairo 1980, Vol. 1: Soil, Food and IndustrialMicrobiol., pp.411-442.

100. Khatibi, A., H.H. Zedan, A.A. Salama and O.M. El-Tayeb (1980). Microbial contamination of non sterile raw materials. III. Contamination with aflatoxin producing fungi. Proc. IVth Conf. Microbiol., Cairo 1980, Vol. I: Soil, Food and Industrial Microbiol., pp. 443-449.

101. Zedan, H.H., O.M. El-Tayeb and M.A. Amin (1980). Transformation of various penicillins by washed cells and nongerminating spores of freshly isolated microbial strains. Sixth International Fermentation Symposium, London. Ontario, Canada, August 1980.

102. Zedan, H.H. O.M. El-Tayeb and M.A. Amin (1980). A feasibility study of the production of 6-aminopenicillanic acid from benzylpenicillin by a local Streptomyces sp. Sixth International Fermentation Symposium, London, Ontario, Canada, August 1980.

103. Zedan, H.H., O.M. El-Tayeb and A.A. Hashem (1980). Isolation and identification of dextran producing microorganisms from Egyptian sugar factories. Egypt. J. Microbiol. 18: 191-204.

104. Zedan, H.H., O.M. El-Tayeb and A.A. Hashem (1980). A quantitative study of the production of dextran from sucrose by a freshly isolated strain of L. mesenteroides. Egypt. J. Microbiol. 18: 205-217

105. Ghalia, M.H., E.M. Salem, S. Shoeb and H.H. Zedan (1979). Synthesis of N-nicotinyl amino acid derivatives with high antitubercular activity. Polish J. Chem. 53: 2239-2250.

106. Hilal, S.H., H.H. Zedan, M.Y. Haggag, F.M. Soliman and S.A. El-Kashoury (1979). The antimicrobial and anticancer activity of Paganumharmala L. Egypt. J. Pharm. Sci. 20: 193-197.

107. Karawya, M.S., M. El-Marzabani, H.H. Zedan, F.M. Soliman, E.A. Moustafa (1979). Phytochemical, antimicrobial, and anticancer screening of Ocimumbasilicum, O canum, and O.rubrum. Egypt. J. Pharm. Sci. 20: 213-219.

108. Abdel-Gawad, A.M., H.H. Zedan, M. Toama (1978). Screening for bio-conversion of antibiotics by various microorganisms. Proc.Ind. Ferment. Symp., Reg. Res. Lab. (CSIR), Jammu Tawi, India,March 1978, pp. 33-41.

109. Abdel-Gawad, A.M., H.H. Zedan, and M. Khadre (1978). Production of 6-aminopenicillanic acid from penicillins by washed mycelium and nongerminating spores of a local streptomycete. Proc. Ind. Ferment. Symp., Reg. Res. Lab. (CSIR), Jammu Tawi, India, March 1978, pp. 42-48.

110. Abdel-Gawad, A.M. and H.H. Zedan (1978). Factors affecting the penicillin acylase activity of the mycelium of a local Streptomyces sp. Proc.Ind. Ferment. Symp., Reg. Res. Lab. (CSIR), JammuTawi, India, March 1978 pp. 49-59.

111. Hilal, S.H., H.H. Zedan, M.Y. Haggag, and F.M. Soliman (1978). Volatile oil of Sequoia sempervirensEndl. Egypt. J. Pharm. Sci. 18: 25- 35.

112. Zedan, H.H. and O.M. El-Tayeb (1977). Microbiological transformations of steroids. IV. Factors affecting the transformation of progesterone by nongerminatingspores of Fusariumsolani. Planta medica31 (2): 163-172.

113. El-Tayeb, O.M., F.E. Murad, H.H. Zedan and A. Abdel-Aziz (1977). Microbiological transformations of steroids. V. Factors affecting the transformation of progesterone by nongerminatingspores of Cylindrocarponradicicola. Planta Medica31 (1): 40-50.

114. El-Tayeb,O.M., A. Khatibi, M. Khadre, and H.H. Zedan (1977). Characteristics of antimicrobial factor(s) produced by a Bacillus pantothenticus strain isolated from Egyptian soil. Bull. Fac. Pharm. Cairo Univ. 14: 65-97.

115. Zedan, H.H., O.M. El-Tayeb, and M. Abdel-Aziz (1976). Microbiological transformations of steroids. I. Transformation by growing mycelia and by mongerminating spores of some fungi. Egypt. J. Pharm. Sci. 17: 213-226.

116. Zedan, H.H., O.M. El-Tayeb, and M. Abdel-Aziz (1976). Microbiological transformation of steroids. II. Transformation of progesterone to 11 & -hydroxyprogesterone by mycelia and by nongerminating spores of an Aspergillus species. Planta Medica30 (3): 251-257.

117. Zedan, H.H., O.M. El-Tayeb, and M. Abdel-Aziz (1976). Microbiological transformations of steroids. III. Transformation of progesterone to androstadiene-dione by the mycelia and by nongerminating spores of two fungi. Planta medica30 (4): 360-368.

118. Nour-Eldin, E.M., Y.E. Hamza, and H.H. Zedan (1975). Solubilization and antimicrobial effect of chloramphenicol. Bull. Fac. Pharm. Cairo Univ. 12: 48-54

119. Abdel-Barry, A., Y.E. Hamza, and H.H. Zedan (1974). Release and antimicrobial properties of iodine incorporated in certain pharmaceutical gels. Bull. Fac. Pharm. Cairo Univ. 13: 77-89.

120. Plourde, R., H.H. Zedan, and J.P. Lamoine (1974). Biotransformation de la progesterone par les spores et les cellules vegetatives de microorganismes provenant du sol Quebecois. Rev. Can. Biol. 33: 111-116.

121. Zedan, H.H. and R. Plourde (1973). Distribution of steroid 1-dehydrogenation and side-chain degradation enzymes in the spores of Fusariumsolani: causes of metabolic lag and carbohydrate independence. Appl. Microbiol. (USA) 25: 650-658.

122. Zedan, H.H. and R. Plourde (1973). Steroid 1-dehydrogenation and side-chain degradation enzymes in the life of cycle of FusariumSolani. Biochem. Biophys. Acta326: 103-115

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