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Lecturer Dr. / Mariam Hassan Abdelmoneam Haikal
Microbiology and Immunology
mariam.hassan@pharma.cu.edu.eg

Latest List of Publications

1. Hassan, M., “Applications of advanced biotechnology in wastewater treatment towards better earth future” Biotechnology Center Earth Day Seminar, Cairo University Earth Day Event, Cairo, Egypt, April 2022. (Oral Presentation)

2. Hassan, M., T. Essam, and S. Megahed, "Orchestration between microalgae and wastewater microbiome in photo-bioreactors established for coking wastewater treatment", The 2nd International Biotechnology Conference, Current Challenges and Future Perspectives” MUST Opera House, Giza, Egypt, Februaury 2022. (Oral presentation)

3. Ibrahim N, Fahim S. Hassan M, Farag A, Georgey H. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: potency and side effects. European Journal of Medicinal Chemistry (2022). 228:114021. https://doi.org/10.1016/j.ejmech.2021.114021

4. Ismail MM, Hassan M, Moawad SS, et al. Exploring the Antivirulence Activity of Pulverulentone A, a Phloroglucinol-Derivative from Callistemon citrinus Leaf Extract, against Multi-Drug Resistant Pseudomonas aeruginosa. Antibiotics (2021). 10(8):907. https://doi.org/10.3390/antibiotics10080907

5. Albash R, Abdellatif MM, Hassan M, Badawi NM. Tailoring Terpesomes and Leciplex for the Effective Ocular Conveyance of Moxifloxacin Hydrochloride (Comparative Assessment): In-vitro, Ex-vivo, and In-vivo Evaluation. Intentional Journal of Nanomedicine (2021), 16:5247-5263. https://doi.org/10.2147/IJN.S316326

6. El-Shiekh RA, Hassan M, Hashem RA, Abdel-Sattar E. Bioguided Isolation of Antibiofilm and Antibacterial Pregnane Glycosides from Caralluma quadrangula: Disarming Multidrug-Resistant Pathogens. Antibiotics (2021), 10(7):811. https://doi.org/10.3390/antibiotics10070811

7. Abdelaziz M, Hassan M, Eldamasy D, Aziz RK, “Retrospective analysis of skin metagenomes for the differential abundance of Malassezia furfur at different skin sites”, 10th International Scientific Conference of the Faculty of Pharmacy, Cairo University- Reshaping Pharma Sustainability and Innovation for Better Pandemic Response Cairo, Egypt, July 2021. (Poster)

8. Al-mahallawi AM, Ahmed D, Hassan M, El-Setouhy DA. Enhanced ocular delivery of clotrimazole via loading into mucoadhesive microemulsion system: In vitro characterization and in vivo assessment. Journal of Drug Delivery Science and Technology (2021), 64:102561. https://doi.org/10.1016/j.jddst.2021.102561

9. Ezzat MI, Hassan M, Abdelhalim MA, El-Desoky AM, Mohamed SO,Ezzat SM. Immunomodulatory effect of Noni fruit and its isolates: insights into cell-mediated immune response and inhibition of LPS-induced THP-1 macrophage inflammation. Food & Function (2021), 12:3170-3179. https://doi.org/10.1039/D0FO03402A

10. Elzeini, H.M.; Ali, A.R.A.A.; Nasr, N.F.; Hassan, M.; Hassan, A.A.m.; Elenany, Y.E., Probiotic capability of novel lactic acid bacteria isolated from worker honey bees gut microbiota. FEMS Microbiology Letters (2021), 368, https://doi.org/10.1093/femsle/fnab030

11. Ali S, Hassan M, Essam M, Ibrahim M, Elamry K. Biodegradation of aflatoxin by bacterial species isolated from poultry farms. Toxicon (2021), 195:7-16. https://doi.org/10.1016/j.toxicon.2021.02.005

12. Salem MA, El-Shiekh RA, Hashem RA, Hassan M. In vivo Antibacterial Activity of Star Anise (Illicium verum Hook.) Extract Using Murine MRSA Skin Infection Model in Relation to Its Metabolite Profile. Infection and Drug Resistance (2021), 14:33-48. https://doi.org/10.2147/IDR.S285940

13. Fahmy AM, Hassan M, El-Setouhy DA, Tayel SA, Al-Mahallawi AM. Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation. Drug Delivery (2021), 28(1):77-86. https://doi.org/10.1080/10717544.2020.1858997

14. Albash R, Al-mahallawi AM, Hassan M, Alaa-Eldin AA. Development and Optimization of Terpene-Enriched Vesicles (Terpesomes) for Effective Ocular Delivery of Fenticonazole Nitrate: In vitro Characterization and in vivo Assessment. Intentional Journal of Nanomedicine (2021), 16:609-621. https://doi.org/10.2147/IJN.S274290

15. Abdelaziz M, Hassan M, Eldamasy D, Aziz RK. Why we missed it? Computational analysis reveals distribution patterns of Malassezia furfur, the etiological agent of Pityriasis versicolor, in skin metagenomes. 25 January 2021, PREPRINT (Version 1) available at Research Square https://doi.org/10.21203/rs.3.rs-122326/v1

16. Fahmy AM, Hassan M, El-Setouhy DA, Tayel SA, Al-Mahallawi AM. Voriconazole Ternary Micellar Systems for the Treatment of Ocular Mycosis: Statistical Optimization and In Vivo Evaluation. Journal of Pharmaceutical Sciences (2020), 17:S0022-3549(20)30792-9. https://doi.org/10.1016/j.xphs.2020.12.013

17. Abd-Elmawla, M, Hassan M, Elsabagh Y, Alnaggar A, Senousy M. Deregulation of long noncoding RNAs ANCR, TINCR, HOTTIP and SPRY4-IT1 in plasma of systemic sclerosis patients: SPRY4-IT1 as a novel biomarker of scleroderma and its subtypes, Cytokine (2020), 133: 155124. https://doi.org/10.1016/j.cyto.2020.155124

18. Hassan A, Hassan M, Nasr N, Ali A, Elenany Y, Elzeini H, “Probiotic capabilities of lactic acid bacteria isolated from the gut microbiota of honey bee Apis mellifera L”, NGU - Biologics & Biosimilars Symposium, Giza, Egypt, March 2020. (Poster)

19. Hassan M, Essam T, Mira A, Megahed S. Biomonitoring detoxification efficiency of an algal-bacterial microcosm system for treatment of coking wastewater: Harmonization between Chlorella vulgaris microalgae and wastewater microbiome, Science of The Total Environment (2019), 677: 120-130. https://doi.org/10.1016/j.scitotenv.2019.04.304

20. Hassan, M., T. Essam, and S. Megahed, "Biomonitoring of photobioreactors established to investigate the impact of toxic load and pollutants variation in coking wastewater treatment: Harmonization between microalgae and wastewater microbiome", 8th Congress of European Microbiologists (FEMS 2019), Glasgow, Scotland, July 2019. (Poster)

21. Hassan, M., T. Essam, and S. Megahed, " Assessing the microbiome dynamics in three photo-bioreactors established for coking wastewater treatment: An orchestration between microalgae and bacterial communities", International Biotechnology and Research Conference, Rome, Italy, April 2018. (Oral presentation)

22. Hassan M, T. Essam, and S. Megahed, “Illumina sequencing and assessment of new cost-efficient protocol for metagenomic-DNA extraction from environmental water samples”, Brazilian Journal of Microbiology (2018), https://doi.org/10.1016/j.bjm.2018.03.002


23. Ismail M.M., M. Hassan, T.M. Essam, "Biological Testing and Toxicity Bioassays in Biodegradation: Toward Better Process Control", In: Bidoia E., Montagnolli R. (eds) Toxicity and Biodegradation Testing, Methods in Pharmacology and Toxicology, Humana Press, New York, NY (2018). https://doi.org/10.1007/978-1-4939-7425-2_9

24. Hassan, M., T. Essam, and S. Megahed, "Community shift of water microbiome in an algal-bacterial based photo- bioreactor for wastewater treatment", 9th Probiotics, Prebiotics & New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health, Rome, Italy, Sep 2017. (Poster)

25. Hassan, M., R. Samir, T. Essam, and S. Megahed, "Biomonitoring of algal-bacterial system for wastewater treatment: Assessment towards better process control", 1st International Conference on Bioresource Technology for Bioenergy, Bioproducts & Environmental Sustainability, Spain, Oct 2016. (Oral presentation)

26. Hassan, M., T. Essam, A. S. Yassin, and A. Salama, "Optimization of rhamnolipid production by biodegrading bacterial isolates using Plackett-Burman design", International Journal of Biological Macromolecules, vol. 82, pp. 573-579, 2016. https://doi.org/10.1016/j.ijbiomac.2015.09.057

27. Hassan, M., A. Yassin, T. Essam, and A. Salama, "Optimized bio-surfactant production by organic pollutants biodegrading bacterial isolates", 3rd FUE International Conference of Pharmaceutical Sciences, Egypt, Feb 2015. (Oral presentation)

28. Hassan, M., A. Yassin, T. Essam, and A. Salama, "Optimization of biosurfactant production using organic pollutants biodegrading bacterial isolates", 2nd International Conference on Advanced basic and Applied sciences, Ain Sokhna, Egypt, April 2014. (Oral presentation)

29. Hassan, M., T. Essam, A. Yassin, and A. Salama, "Screening of Bio-Surfactant Production Ability among Organic Pollutants Degrading Isolates Collected From Egyptian Environment", Journal of Microbial and Biochemical Technology, vol. 6, issue 4, pp. 195-201, 2014.

30. Hassan, M., A. Yassin, T. Essam, and A. Salama, "Screening of relevant biodegrading bacterial isolates for the production of biosurfactants", 3rd International Scientific Conference of the Faculty of Pharmacy, Cairo University, Egypt, April 2012. (Poster)
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